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Your Early-Stage
Research Experts

Fully Customizable. Faster Results. Better Predictability

We Are Hera BioLabs

Seasoned Researchers Generating Transformative
Data and Products for R&D

At Hera, we leverage a 15+ year history of gene engineering advancements to create better models and be your preclinical research partner of choice. Our proprietary family of platforms includes:

  • SRG Rat® Platform–the first commercially available highly immunodeficient rat model optimal for human xenograft studies

  • piggyBac® Non-viral DNA Delivery Platform–a trusted system for cell line engineering and transgenesis, validated by 750+ peer-reviewed publications.
  • Cas-CLOVER™ Site-Specific Gene Editing Platform–a proven alternative to CRISPR/Cas9 with accessible licensing options.

Combined with these proprietary platforms, our experienced team, modern facilities, and portfolio of sophisticated research tools and services deliver robust, high-quality data to accelerate drug discovery and development.

Our Work Supports Advancements In:

Compliment Your Research
with Our Expertise

SRG Rat®
SRG Rat

Use our proprietary platform to advance your preclinical program

Xenograft Services
SRG Rat

Benefit from our in-house expertise and comprehensive xenograft portfolio

In Vivo Services
SRG Rat

Seamlessly evaluate efficacy and early safety with our in-house capabilities

Cell Line Development
SRG Rat

Ideal for producing your protein across research and biomanufacturing applications

Gene Editing Services
SRG Rat

Commission improved cell lines and animal models using our unique gene editing technology

Gene Editing Reagents
SRG Rat

Already using our platforms for drug discovery in-house? Get the reagents you need online

Hera’s SRG Rat®

A Smarter Choice for Oncology Insights

To meet the industry’s need for a larger rodent model with a high probability of attaining successful cell line-derived xenografts and PDXs of sufficient size for serial biopsies, Hera developed and validated a platform in vivo model called the SRG Rat®. A SCID rat of the Sprague Dawley background engineered to house a double knockout of the Rag2 and Il2rγ genes, the SRG Rat® has proven applications in oncology, infectious diseases, and other areas of pharmacology/toxicology.

To further accelerate your R&D, our team provides in vivo services at Hera BioLabs and rapid delivery of the SRG Rat through the global network of Charles River.

Researcher Spotlight

Prostate Cancer Research with the SRG Rat®

“The tumor uptake rate was 80-100%, which is a huge advantage because what we could achieve as statistical significance with 8-12 mice, can be achieved with 5-6 SRG Rats®.”

Ramesh Narayanan, Ph.D. Associate Professor of Medicine & Hematology at the University of Tennessee Health Science Center

Advance Your Gene Editing

Make Progress with Our Novel Technologies

Gene editing expertise and proprietary technology are core to Hera’s history and the secret to our advanced gene-editing toolbox. Our platforms’ portfolio of successes includes building 100+ custom-engineered cell lines- from knockouts and knock-ins to stable cell lines and reliably accelerating R&D activities.

Hera’s proprietary Cas-CLOVER™ Site-Specific Gene Editing Platform efficiently builds custom-designed nucleases and executes cell modifications such as knockouts/ins.

Our exclusive piggyBac® Non-viral DNA Delivery Platform for early-stage research accelerates drug discovery through the rapid creation of disease-relevant models and tailored cell lines.

The Industry Standards for
Gene Editing Tools

Our technology has been featured in 800+ papers including the high-impact publications below.

See how Hera’s technology and staff are assisting researchers globally in solving complex problems and producing robust data.

Hera’s Lexington Facility

AAALAC Accredited. Independent. US-Based.

Strategically located, our headquarters and facility in Lexington, Kentucky, USA, house the latest in gene editing technology and animal care. Our on-site barrier-level vivarium was designed to house immunodeficient models and features the Innovive Innorack® and Innocage® dual HEPA-filtered, disposable IVC rodent caging system.

Our Commitment

To The Animals in Our Care

We are grateful to the animals who have helped us attain critical preclinical data to move projects into clinical development for the improvement of patient lives. We are devoted to their ethical care and honor their service to science.

Our AAALAC Accredited Animal Welfare Program and our commitment to fostering a culture of care for the animals we work with are deeply rooted in the Replacement, Reduction, and Refinement ethical framework of modern research.

If you would like to learn more, please visit our Facilities/Vivarium page.

“The Council commends [Hera for] maintaining an exemplary program of laboratory animal care and use. Especially the [team’s] strong administrative commitment to the program and to attaining accreditation, …the investments in infrastructure, equipment, and personnel, [and their] excellent documentation, and standard operating procedures…”

Our Latest

Insights From Hera’s Team

Learn from our experts with thought leadership content about Hera’s latest R&D efforts and CRO industry trends.

Ready To Advance Your Research?

Let’s Talk

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