The SRG rat™ possesses published characteristics that may complement or overcome the limitations of the Nude rat and SCID mice such as nude mice, NOD SCID mice and NSG mice. Publications are broken down by application including xenograft models and tumor models, humanized immune system for immuno-oncology studies and preclinical trials. Hera, its collaborators and customers are continuing the development and adoption of the SRG rat in different research areas and will update this page accordingly.
Cancer Xenograft Model
2017 American Association for Cancer Research (AACR) Annual Meeting poster A Novel Immunodeficient Rat for Modeling Human Cancer.
2017 American Association for Cancer Research (AACR) Advances in Modeling Cancer in Mice. Novel immunodeficient rat models capable of supporting the growth of human tumor xenografts. This poster includes ovarian patient derived xenograft or PDX model data in SRG rat and NSG mice.
Humanized immune system and immune-oncology in the SRG rat
2017 AACR-EORTC-NCI Molecular Targets poster Novel immunodeficient rat models offers a unique platform for drug efficacy studies in human tumor xenografts.